Endocrine Abstracts

Background: Type 2 diabetes mellitus (T2DM) is becoming increasingly prevalent in children and young people (CYP), mainly linked to the rise in obesity. It is associated with higher and earlier risk of developing complications; therefore, prompt diagnosis and management involving the multidisciplinary team (MDT) is crucial. The aim of our study was to evaluate the current practice for T2DM management and monitoring of complications at our centre.Methods:...

Introduction: Cataract development as a complication of diabetes is usually associated with increased age and longer duration of diabetes. However, rapidly progressive cataracts have also been described at, or soon after, diagnosis of type 1 diabetes (T1DM). We report two cases of adolescents with T1DM and bilateral cataracts, including one case in which visual loss was the presenting symptom.Cases: A 16-year old non-obese, caucasian boy presented to his...

Introduction: Pancreatogenic diabetes (Type 3c diabetes-T3cDM) is rare in children, and frequently underdiagnosed. The prevalence is 5–10% of all adult diabetes cases in the developed world. Over 78% of people with T3cDM have chronic pancreatitis.Case: A 15-year old presented with polyuria, polydipsia, abdominal pain, weight loss (WL) and a three-generational family history of type-1 (T1DM) and type-2 diabetes mellitus (T2DM). Examination revealed m...

Introduction: Childhood Adrenocortical tumours (ACTs) are rare neoplasms of the adrenal glands, accounting for 0.2% of all childhood cancers. Cases are mainly sporadic, but some mutations have been identified. ACTs are usually benign unilateral adenomas, but rare malignant carcinomas have poor prognosis. We present a case of adrenal insufficiency following a unilateral adrenalectomy for a functioning adrenocortical adenoma in a child.Case: A 15 month old...

Introduction: The Flash glucose monitoring system (FGS) has recently received a licence for children and young people aged 4–17 years with Type 1 diabetes (T1D) in the United Kingdom. Although many families attending a single UK diabetes centre reporting utilising FGS even prior to its licence we aimed to assess the patient experience.Methods: Patients and families were invited to undertake a 14 day FGS trial following group introductory sessions. 8...

Introduction: Children with Down syndrome (trisomy-21/T21) are at risk of developing congenital and early (diagnosed ≤1 year) hypothyroidism. Our current monitoring follows the Down Syndrome Medical Interest Group (DSMIG) guidance: performing thyroid function tests (TFT) at birth and 12 months.Aims/objectives: 1) Determine the incidence of congenital/early hypothyroidism in babies with T21 and determine long-term thyroid function outcomes (by age 4...